Occasionally, polymorphonuclear leukocytes are seen in severe cases. Macrophages then infiltrate and migrate to the myelin sheath, eventually causing the destruction of myelin sheaths.
Macrophage and polymorphonuclear neutrophilic leukocytes (PMN) are essentially involved in the immune response of the body.
Motor deficit may begin proximally or distally in the extremities and sensory deficit is sometimes, but not always present.
Some cases have a dramatic and rapid deterioration, whereas others have a more subacute onset.
Dehydration and undernutrition may result.
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